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Vitamin A levels and growth hormone axis / R Raifen; Y Altman; Z Zadik.-- pp.279-281.-- En: Hormone Research.-- 46, 6 (1996)
PROTEINAS PORTADORAS   NIÑO   INFANTE   RITMO CIRCADIANO   ESTUDIOS DE SEGUIMIENTO   PROTEINA DE ENLACE DE FACTOR DE CRECIMIENTO   SIMILAR A LA INSULINA   FACTOR I DEL CRECIMIENTO SIMILAR A LA INSULINA   SOMATROPINA   VITAMINA A
Ubicación: Centro de Información y Documentación (CANIA)   
Solicite el material por este código: AS-4958
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    Vitamin A (VA) is required for normal growth and development retinoic acid may be the active metabolite through binding to nuclear receptors. Recently a correlation between nocturnal growth hormone (GH) secretion and VA was was found in short slowly growing children. We determined the 24-hour integrated concentration of GH (IC-GH), GH response to provocative stimuli, IGF-I, IGF-binding protein-3 (IGF-BP3) and GH-binding protein (GH-BP) in 34 prepubertal children (25 m/9 f) 5-10 years of age, height -2.5 to 1.5 SDS and body mass index -1.5 to 1.5 SDS for age and sex. Since folic acid, vitamin B12, IGF-I, cholesterol, triglycerides and VA carrier proteins were normal we assumed that no major nutritional deficiency existed. The correlation matrix of the variates tested were p < 0.05 for VA and IC-GH and p < 0.006 for IGF-BP3. It is suggested that VA might have a direct affect on both ICGH and IGF-BP3.-

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