Management of pre-eclampsia / L Duley; S Meher; E Abalos.-- pp. 463-68.-- En: British Medical Journal.-- 332, 7539 (2006)
Ubicación: Centro de Información y Documentación (CANIA)   
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    Pre-eclampsia is part of a spectrum of conditions known as the hypertensive disorders of pregnancy (box 1).1 A multisystem disorder usually associated with raised blood pressure and proteinuria, pre-eclampsia is relatively common, affecting 2-8% of pregnancies. Although outcome is often good, pre-eclampsia can be devastating and life threatening for both mother and baby (box 2), particularly in developing countries.2 It may also lead to an increased risk of cardiovascular disease in later life. Although the cause is not fully understood, factors thought to have a role include genes, the placenta, the immune response, and maternal vascular disease.3 Inadequate blood supply to the placenta leads to endothelial dysfunction, which accounts for the secondary changes in maternal target systems (such as platelet aggregation and vasoconstriction) responsible for the signs and symptoms of pre-eclampsia (box 3). Effective care includes identification and referral of women at high risk, prompt diagnosis with prevention and treatment of complications, and timely delivery (the only definitive cure). This review summarises current evidence on management of pre-eclampsia.

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